Explore our premium factory-grade chemical formulations for agricultural and public health vector control.
An in-depth analysis of Second-Generation Anticoagulant Rodenticide (SGAR) mechanisms, matrix stability, and palatability optimization.
Brodifacoum (CAS No. 56073-10-0) represents the pinnacle of 4-hydroxycoumarin derivative chemical engineering. As a highly potent Second-Generation Anticoagulant Rodenticide (SGAR), its molecular mechanism centers on the irreversible inhibition of the enzyme Vitamin K1 epoxide reductase (VKOR). This enzymatic blockade prevents the regeneration of Vitamin K1 hydroquinone, interrupting the post-translational gamma-carboxylation of essential blood coagulation factors (II, VII, IX, and X). The physiological result is a systemic disruption of the vascular clotting cascade, culminating in painless internal hemorrhage and rodent death over a 3 to 7-day period.
Information Gain Insight: Unlike first-generation anticoagulants (e.g., Warfarin, Coumatetralyl) which require multi-day sequential feeding, Brodifacoum features an exceptionally high receptor binding affinity. A single consumption event containing as little as 0.27 mg/kg (LD50 in Rattus norvegicus) delivers a lethal dose. The delayed physiological onset is structurally critical to prevent bait shyness within established rodent colonies.
As a leading Chinese pesticide and public health vector control manufacturer, our chemical manufacturing facility engineers specialized bait matrices customized for diverse global climate zones and species behaviors:
Formulated with high-melting-point synthetic food-grade paraffin and microencapsulated Brodifacoum active tech. Engineered specifically for high-humidity environments, sewer systems, and tropical agricultural fields. Resistant to fungal degradation and water erosion.
Utilizes human-food grade crushed wheat, oat, or rice matrix impregnated with 0.005% Brodifacoum. Features specialized flavor enhancers and kairomones that simulate natural grain sources, ensuring rapid consumption in indoor grain storage, silos, and commercial warehouses.
High-lipid oil-based paste formulations packaged in permeable filter-paper sachets. Designed specifically for environments with rich competing food sources, such as food processing plants and livestock facilities where traditional grain baits face acceptance challenges.
| Technical Parameter | Brodifacoum Technical Grade (TC) | Brodifacoum Bait Formulations (CB / RB / BB) |
|---|---|---|
| CAS Registry Number | 56073-10-0 | Formulated Product Matrix |
| Active Concentration | 95% TC / 98% TC Minimum | 0.005% (50 mg/kg) standard active loading |
| Appearance | Off-white to light yellow powder | Blue, Red, or Green extruded blocks/pellets |
| Safety Additive | N/A | 10 ppm Denatonium Benzoate (Human Aversion Bitterant) |
| Target Pests | N/A | Rattus norvegicus, Rattus rattus, Mus musculus |
| Thermal & UV Stability | Stable under standard ambient storage | 24-Month minimum shelf-life in sealed barrier packaging |
Leveraging Hebei agrochemical chemical synthesis hubs for global supply chain security, cost control, and rigorous QA/QC oversight.
Located in Shijiazhuang, Hebei Province—the core of China's agrochemical manufacturing corridor. Direct access to essential precursor compounds enables full vertical integration, shielding global buyers from market price volatility and ensuring consistent high-purity batch synthesis.
Our facility utilizes fully enclosed computerized continuous extrusion lines. Active ingredient dispersion is monitored via real-time online spectroscopy, ensuring strict homogeneous distribution of the 0.005% Brodifacoum active throughout every gram of bait matrix.
We provide enterprise procurement partners with complete regulatory support dossiers, including FAO/WHO specification compliance certificates, ISO 9001/14001 certification, full HPLC active ingredient assay reports, and GLP-accredited eco-toxicity test data.
Tailored vector management strategies for municipal health, industrial agriculture, port biosecurity, and commercial facilities.
Rodents cause devastating post-harvest food losses globally. In grain storage silos and transit centers, Brodifacoum grain baits are deployed in perimeter tamper-resistant bait stations (TRBS). Placing stations at 5 to 10-meter intervals along wall-floor junctions creates an impenetrable barrier, preventing rodent migration into bulk storage reserves without contaminating human food supplies.
Poultry houses and swine farms present high-challenge environments due to abundant feed competition and warm nesting sites. Rodents act as primary vectors for Salmonella enterica, African Swine Fever, and Avian Influenza. We supply highly attractive paraffin soft-baits designed to out-compete commercial animal feed while enduring high farm humidity.
Urban sewer systems house dense populations of Norway rats (Rattus norvegicus). Damp conditions wash away standard grain baits within hours. Our heavy-duty paraffin wax blocks are wired directly to sewer manhole ladders or drainage pipes, maintaining structural stability and lethal efficacy despite continuous moisture contact.
International maritime regulations mandate strict shipboard rodent control to eliminate vessel-borne disease transmission and wiring damage. Specialized, tamper-proof Brodifacoum bait modules are deployed along cargo holds, engine rooms, and dockside container yards in compliance with International Health Regulations (IHR 2005).
Navigating environmental regulations, non-target species protection, and smart digital vector monitoring.
Global regulatory agencies (EU BPR, US EPA) demand enhanced safeguards against non-target primary poisoning. Next-gen Brodifacoum manufacturing incorporates high-potency human aversion agents (such as 10ppm Denatonium Benzoate) alongside fluorescent tracer dyes, allowing operators to visually track rodent feces and verify bait ingestion.
Professional Pest Control Operators (PCOs) are moving toward digital rodent monitoring. Modern Brodifacoum bait installations now integrate with optical sensors and IoT weight plates inside secure stations, alerting pest controllers instantly when bait consumption occurs to optimize replenishment cycles.
Where first-generation anticoagulant resistance is confirmed (e.g., VKORC1 gene mutations in urban rodent strains), Brodifacoum remains the gold standard absolute lethal rotation partner. Global B2B buyers rely on our customized batch formulations to eliminate resistant populations efficiently.
Delivering high-purity chemical syntheses and global supply security since 2006.
Awiner Biotech was founded in 2006, located in the north of China—Shijiazhuang, Hebei Province. The city is in close proximity to China's capital, Beijing, providing streamlined logistical connections to major ocean ports including Tianjin and Qingdao.
Awiner Biotech is dedicated to the research, synthesis, formulation, and global export distribution of advanced agrochemicals. Our comprehensive product portfolio spans high-potency insecticides, public health vector control solutions, rodenticides, herbicides, fungicides, and plant growth regulators.
Up to now, we have established long-term strategic supply partnerships across global markets including Iraq, Iran, Afghanistan, Pakistan, India, Libya, Syria, Turkey, Yemen, Ukraine, Russia, Kazakhstan, Uzbekistan, Chile, Bolivia, Mexico, Brazil, Paraguay, Nigeria, Djibouti, Rwanda, Somalia, Malaysia, Cambodia, Nepal, Myanmar, and beyond.
Our international technical team participates in regional industry exhibitions worldwide (including Turkey, Russia, Nigeria, Uzbekistan, and Malaysia) and regularly conducts field inspections in client countries to analyze efficacy data, optimize packaging for local market conditions, and resolve regulatory hurdles.
Technical, regulatory, and logistical details for enterprise procurement managers and agricultural distributors.
Consolidate your global chemical sourcing with our complete range of insecticides, herbicides, and rodent control products.
Awiner Biotech
