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An in-depth industrial breakdown of Cyprodinil (CAS No. 121552-61-2), its biochemical mode of action, multi-pathway disease eradication capability, and advanced formulation physics.
Cyprodinil (4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine) is a broad-spectrum, systemic fungicide belonging to the anilino-pyrimidine (AP) chemical class. Classified under FRAC Group 9, Cyprodinil operates through a distinct biochemical pathway by inhibiting the biosynthesis of methionine—an essential amino acid required for fungal protein synthesis and cellular elongation.
Unlike triazole fungicides that target ergosterol synthesis (FRAC 3) or strobilurins that disrupt mitochondrial respiration (FRAC 11), Cyprodinil disrupts the secretion of hydrolytic fungal enzymes (such as cell wall-degrading pectinases, cellulases, and laccases) required for host tissue penetration. This dual action prevents initial germ tube elongation and appressoria formation, making it exceptionally effective as both a protective barriered application and an early-stage curative treatment against phytopathogenic ascomycetes and deuteromycetes.
As a specialized wholesale Cyprodinil agrochemical manufacturer, our research laboratory focuses on overcoming physical stability barriers inherent in pure Cyprodinil technical material (TC purity ≥ 98%). Cyprodinil possesses a melting point of 75.9°C and low water solubility (13 mg/L at pH 7, 25°C), requiring precise surfactant pairing and particle size control during industrial formulation.
| Formulation Type | Active Concentration | Key Surfactants & Co-formulants | Physical Technical Specifications |
|---|---|---|---|
| Cyprodinil 75% WDG | 750 g/kg | Sodium lignosulfonate, Alkylnaphthalene sulfonate condensate | Dispersibility > 90%, Wetting time < 30s, Particle D90 < 5μm, Suspension rate > 85% |
| Cyprodinil 50% WDG | 500 g/kg | Polycarboxylate dispersants, Modified silicon antifoam | Dust-free micro-granules, zero crystallization at 54°C thermal storage test (14 days) |
| Cyprodinil + Fludioxonil WDG | 37.5% + 25% | Dual-action stabilizer matrix, Naphthalene sulfonate blend | Synergistic Botrytis control, high rainfastness within 2 hours of field application |
| Cyprodinil 300g/L SC | 300 g/L | Tristyrylphenol ethoxylate phosphate, Propylene glycol | Viscosity 400-800 mPa·s, particle size D50 < 1.8μm, zero phase separation |
Why international distributors and multinational agrochemical brands partner with our Shijiazhuang manufacturing ecosystem for bulk Cyprodinil synthesis.
Our strategic manufacturing location in Hebei provides direct pipeline integration with key intermediate producers for 2-amino-4-methyl-6-cyclopropylpyrimidine. This backward-integrated supply chain eliminates raw material bottlenecks, guaranteeing constant batch production even during peak agricultural seasons.
Utilizing fully automated continuous flow synthesis reactors and modern fluid-bed granulation equipment, our plant achieves superior batch-to-batch uniformity. High-shear wet granulation ensures that Cyprodinil WDG products maintain structural integrity without dusting while retaining instantaneous dissolution capability.
Equipped with Zero Liquid Discharge (ZLD) wastewater purification, high-temperature thermal oxidizers (TO) for VOC containment, and ISO 14001 certification, our production runs continuously without risk of regulatory shutdown, protecting your long-term supply chain security.
Tailored application protocols engineered to deliver high efficacy across diverse climatic zones and crop disease pressures.
Target: Botrytis cinerea (Gray Mold).
Dosage: 500-750 g/ha (75% WDG).
Timing: Pre-coopering, veraison, and 21 days prior to harvest. Offers rapid rainfastness and preserves berry berry-skin integrity without affecting fermentation yeasts.
Target: Venturia inaequalis.
Dosage: 300-400 g/ha.
Timing: Green tip to pink bud stage. Cyprodinil provides exceptional low-temperature activity (active at 5°C-10°C), outperforming triazoles in cold early spring windows.
Target: Monilinia fructicola / laxa.
Dosage: 450-600 g/ha.
Timing: Blossom blight application during early bloom followed by pre-harvest protection. Prevents latent storage rot during cold-chain shipping.
Target: Pseudocercosporella herpotrichoides (Eyespot), Pyrenophora teres.
Dosage: Formulated as seed dressing SC.
Benefit: Controls seed-borne pathogens and shields early tiller development against soil-borne inoculum.
End-to-end commercial manufacturing solutions tailored for agrochemical importers, formulators, and brand distributors globally.
We provide comprehensive GLP-accredited data packages, including 5-batch chemical analysis, acute toxicology studies (oral, dermal, inhalation, skin/eye irritation), mutagenicity screening, and environmental fate profiles (ecotox on bees, aquatic organisms, algae) required for ministry registration (ICAMA, EU REACH, EPA, SENASA, MAPA).
Custom packaging capabilities tailored to distribution channels: bulk packaging in 25kg aluminum foil bags, fiber drums, 500kg super sacks, or retail-ready water-soluble bags (PVA), 100g-1kg customized printed pouches, and rigid HDPE bottles for liquid formulations with full UN HazMat safety compliance.
Every shipment undergoes rigorous quality verification utilizing High-Performance Liquid Chromatography (HPLC) for active assay content, CIPAC MT 177 for wet sieving, CIPAC MT 184 for dispersibility, and Karl Fischer titration for moisture control. Batch Samples are archived for 2 years post-shipment.
Founded in 2006 in Shijiazhuang, Hebei Province, China—delivering world-class crop protection solutions to over 50 countries worldwide.
Awiner Biotech has evolved into a leading specialized synthetic manufacturer and exporter of crop protection products. Situated close to Beijing, our logistical advantage connects our state-of-the-art production base directly with major shipping ports (Tianjin and Qingdao), ensuring rapid export response times. We specialize in research, formulation development, and international marketing of high-tier pesticides, selective herbicides, advanced fungicides, plant growth regulators (PGRs), and public health vector control chemicals.
Up to now, we have won trusted customers across key agricultural markets: Iraq, Iran, Afghanistan, Pakistan, India, Libya, Syria, Turkey, Yemen, Ukraine, Russia, Kazakhstan, Uzbekistan, Chile, Bolivia, Mexico, Brazil, Paraguay, Nigeria, Djibouti, Rwanda, Somalia, Malaysia, Cambodia, Nepal, Myanmar, and beyond.
Our commercial and technical engineering teams actively participate in premier global agrochemical exhibitions worldwide, including events in Turkey, Iran, Pakistan, Nigeria, Russia, Cambodia, Malaysia, Uzbekistan, and CAC China.
We conduct in-person market inspections across client territories to analyze specific localized disease pressures, troubleshoot tank-mix compatibilities, evaluate spray equipment performance, and host technical seminars for regional distributors.
Expert answers regarding Cyprodinil chemistry, anti-resistance strategies, tank-mix compatibility, and procurement logistics.
Complete your inventory with our broader spectrum of high-performance technical formulations for global agricultural crop protection.
Awiner Biotech