High-efficacy crop protection, public health insecticides, and specialized defoliants directly from China's primary manufacturing hub.
Unlocking maximum defoliation efficacy and boll opening velocity through dual-action physiological pathways.
In modern intensive agriculture, particularly mechanical cotton harvesting, the combination of Thidiazuron (TDZ, CAS 51707-55-2) and Diuron (CAS 330-54-1) represents the gold standard for harvest aid systems. Thidiazuron functions as a highly potent substituted phenylurea plant growth regulator exhibiting strong cytokinin-like activity. Upon foliar absorption, TDZ triggers the synthesis of endogenous ethylene within the petiolar tissues while simultaneously inhibiting auxin transport from the leaf blade. This physiological shift accelerates the formation of a distinct abscission layer at the base of the leaf stem, causing green, intact leaves to shed naturally without desiccation or foliage freeze.
However, standalone Thidiazuron applications can suffer from temperature sensitivity, requiring ambient thermal conditions above 20°C to achieve full efficacy. This is where Diuron acts as a decisive biochemical catalyst. As a photosystem II (PSII) electron transport inhibitor, Diuron disrupts photosynthesis at the thylakoid membrane level, accelerating leaf senescence and enhancing TDZ's signal transduction pathways. When combined in optimized ratios (such as TDZ 360g/L + Diuron 180g/L SC or TDZ 120g/L + Diuron 60g/L SC), the two compounds exhibit extraordinary synergy:
TDZ stimulates the 1-aminocyclopropane-1-carboxylic acid (ACC) synthase pathway, ramping up internal ethylene biosynthesis to stimulate clean leaf dropping within 7 to 10 days post-application.
Diuron prevents light energy conversion, producing reactive oxygen species (ROS) in targeted foliage. This forces rapid chlorophyll degradation, priming the abscission zone for clean detachment.
Unlike classic desiccant herbicides (e.g., Paraquat or Diquat), TDZ+Diuron maintains systemic hormonal suppression, preventing terminal and lateral buds from sprouting secondary leaves before mechanical pickers pass.
Desiccated, crispy leaves caused by low-quality defoliants break into fine trash during spindle picking, permanently staining raw cotton lint and reducing market grade. Awiner Biotech's micro-milled Thidiazuron + Diuron SC formulations ensure leaves drop while still pliable, leaving clean cotton bolls open to solar drying and achieving zero leaf trash contamination.
Rigorous quality control matrix for Chinese export-grade Thidiazuron and Diuron products.
| Parameter / Specification | Thidiazuron Technical (98% TC) | Diuron Technical (97% TC) | TDZ + Diuron 540g/L SC | TDZ 50% WP / WDG |
|---|---|---|---|---|
| CAS Registry Number | 51707-55-2 | 330-54-1 | Mixture (51707-55-2 + 330-54-1) | 51707-55-2 |
| Active Ingredient Content | ≥ 98.0% w/w | ≥ 97.0% w/w | TDZ 360g/L + Diuron 180g/L | ≥ 50.0% w/w |
| Appearance | Off-white to light yellow powder | White crystalline solid | Viscous off-white flowable liquid | Fine light gray dispersible powder |
| pH Range | 5.0 - 8.0 | 6.0 - 8.0 | 5.0 - 8.0 | 6.0 - 9.0 |
| Suspensibility / Dispersion | N/A | N/A | ≥ 95% Suspensibility | ≥ 90% Wetting time < 60s |
| Moisture / Water Content | ≤ 0.5% | ≤ 0.5% | N/A (Aqueous base) | ≤ 2.0% |
| Particle Size (D90) | ≤ 45 μm | ≤ 45 μm | ≤ 3.5 μm (Laser Particle Sizer) | ≤ 15 μm |
Using ultra-fine wet grinding technology, Awiner Biotech reduces particle sizes down to sub-3-micron levels. This guarantees zero nozzle clogging in agricultural spray drones and high-boom tractor sprayers, while maximizing foliar adhesion and rainfastness.
Our water-dispersible granules (WDG) utilize advanced fluid-bed granulation technology, eliminating dust hazards during field mixing, offering rapid 30-second disintegration, and maintaining long-term physical stability under tropical storage conditions.
Pre-mixed with organosilicone penetrants and anti-evaporation agents, our formulations break leaf surface tension on waxy cotton leaves, ensuring rapid bio-absorption even in low-humidity environments.
Next-generation delivery systems, drone-compatible formulations, and sustainable chemical synthesis.
With the global explosion of UAV (Unmanned Aerial Vehicle) spraying in regions like Xinjiang, Latin America, and Southeast Asia, conventional high-volume tank mixtures face drift and evaporation challenges. Awiner Biotech is engineering specialized Ultra-Low Volume (ULV) TDZ+Diuron nano-emulsions that resist drift, maintain micron-droplet integrity, and achieve 99% coverage at water volumes as low as 15-20 L/hectare.
To align with strict EU and LATAM environmental safety regulations, our synthesis labs are replacing petroleum-derived aromatic solvents with methyl esterified vegetable oil bases. This reduces volatile organic compound (VOC) emissions during field spraying while improving cuticle lipid layer penetration without crop phytotoxicity.
Traditional TDZ applications fail when night temperatures drop below 15°C. Awiner Biotech's patented cold-active adjuvants stimulate plant membrane fluidity, enabling effective cotton defoliation even during unseasonable early-autumn cold snaps in northern farming zones.
Tailored agronomic strategies for mechanical harvesting across diverse climate zones.
Target Regions: Central Asia (Uzbekistan, Kazakhstan), Middle East, Northwest China.
Challenge: Leaves dry out rapidly before forming an abscission layer, resulting in foliage hanging on stems.
Solution: Lower Diuron proportion, add non-ionic wetting agents, and spray in late afternoon to maintain leaf turgor pressure during hormonal action.
Target Regions: South America (Brazil, Paraguay), South Asia.
Challenge: Rain wash-off within hours of application and vigorous late-season regrowth.
Solution: High-concentration TDZ+Diuron SC with integrated organosilicone rainfast adhesives. Ensures complete foliar uptake within 2 hours of application.
Target Regions: Eastern Europe, Northern Russia, high-latitude cotton fields.
Challenge: Rapidly falling temperatures delay boll opening and defoliation.
Solution: Tank-mix TDZ+Diuron with Ethephon (ethrel) boll openers to simultaneously force leaf abscission and accelerate fiber maturation before first frost.
Vertical integration from raw chemical intermediates to global port logistics.
China produces over 80% of the world's Thidiazuron and Diuron technical active ingredients. As a leading manufacturer based in Shijiazhuang, Hebei Province, Awiner Biotech leverages the full structural advantages of China's chemical industrial parks:
Direct sourcing of core synthesis intermediates (such as phenyl isocyanate and 3,4-dichloroaniline) ensures complete protection against raw material price shocks and continuous year-round manufacturing capacity.
State-of-the-art DCS-controlled chemical reactors guarantee batch-to-batch consistency with technical purity exceeding 98.0%, minimal isomer impurities, and zero heavy metal contamination.
Our facilities operate zero-liquid-discharge (ZLD) wastewater purification systems and thermal oxidizers for exhaust gases, ensuring compliance with strict national environmental standards and zero plant shutdowns.
Located near Beijing with direct high-speed freight access to northern China's major sea hubs, we guarantee container loading, hazardous goods clearance (DG packaging), and vessel departure within 7-14 days.
Understanding price dynamics, seasonal procurement windows, and custom OEM packaging solutions.
Global TDZ and Diuron prices follow agricultural seasonal cycles. Peak demand occurs from May to August (northern hemisphere cotton preparation). Procurement contracts locked in Q4 and Q1 deliver cost savings of 8% to 15%.
Standard FOB/CIF bulk orders start at 1,000 Liters / 1,000 kg. Full Container Load (FCL 20ft: ~16,000L in drums or 14,000 kg in small bottles) unlocks tier-one factory-direct pricing with customized labeling.
We offer tailored packaging ranges: from 100mL, 500mL, 1L HDPE/Coex fluorinated bottles for retail distribution to 20L, 200L UN-rated steel/HDPE drums and 1000L IBC totes for large commercial farming operations.
Empowering global distributors with complete registration support, GLP reports, and compliance data.
Navigating foreign agricultural regulatory bodies requires comprehensive dossier support. Awiner Biotech's dedicated regulatory affairs team provides complete regulatory packages to ensure seamless product registration in importing nations across Latin America, Africa, the Middle East, and Eastern Europe:
Full GLP-certified 5-batch analysis reports, impurity profiling, physical-chemical property testing, and CIPAC method validation for both technical active ingredients and end-use formulations.
Complete toxicology summaries (acute oral, dermal, inhalation, eye/skin irritation, sensitization) alongside ecotoxicology assessments (birds, aquatic organisms, bees, earthworms) meeting FAO/WHO standards.
Official Ministry of Agriculture (ICAMA) registration certificates, Certificates of Free Sale (CFS), legalised COA (Certificate of Analysis), and MSDS compliant with GHS global standards.
Multi-location field trial reports proving crop safety, defoliation kinetics, and leaf drop percentages across varying soil and meteorological conditions.
Discover Awiner Biotech's legacy, manufacturing strength, and worldwide distribution network.
Awiner Biotech was founded in 2006, located in north of China-Shijiazhuang, Hebei Province. The city is close to our capital Beijing, transportation is convenient. Awiner Biotech is committed to research, produce and distribute agrochemicals, mainly dealing with pesticides, herbicides, fungicides, plant growth regulators and public health pesticides.
With over two decades of dedicated agrochemical synthesis expertise, our state-of-the-art facilities ensure that every batch of plant growth regulators, insecticides, and crop health formulations meet international FAO and WHO standards.
Up to now, we have won customers from Iraq, Iran, Afghanistan, Pakistan, India, Libya, Syria, Turkey, Yemen, Ukraine, Russia, Kazakhstan, Uzbekistan, Chile, Bolivia, Mexico, Brazil, Paraguay, Nigeria, Djibouti, Rwanda, Somalia, Malaysia, Cambodia, Nepal, Myanmar and so on.
Our countries participating in the exhibition are Turkey, Iran, Pakistan, Nigeria, Russia, Cambodia, Malaysia, Uzbekistan, etc., maintaining face-to-face engagements with global agricultural distributors.
We go to the customer's country to conduct market inspections, analyze and solve problems for them, understand their product usage, and customers will also visit our manufacturing plants in Hebei.
Expert technical answers addressing commercial procurement, field dosage, safety, and application protocols.
The most commercially proven ratio is 2:1 (Thidiazuron : Diuron). Standard commercial formulations include TDZ 360g/L + Diuron 180g/L SC (540g/L total) or TDZ 120g/L + Diuron 60g/L SC. This 2:1 balance maximizes ethylene-induced leaf detachment while using Diuron to inhibit leaf photosynthesis and regrowth without causing foliar freeze or leaf burning.
Thidiazuron is a hormone-mimicking compound that relies on active plant metabolism; thus, performance drops significantly when daytime temperatures fall below 18°C. Combining TDZ with Diuron reduces this thermal dependency. For cold autumn climates, adding specialized tank-mix adjuvants or co-applying with Ethephon accelerates boll opening and foliage drop even under lower thermal conditions.
Application should occur when cotton boll opening reaches 60% to 70%, and the youngest harvestable top boll is mature (seeds have darkened seed coats and cotyledons are fully formed). Applying too early can reduce seed weight and fiber micronaire, while applying too late reduces defoliation efficiency due to cooler temperatures.
While WP formulations are cost-effective, SC formulations offer superior dispersion, smaller micron-sized particles, zero operator dust exposure, and greater rainfastness. Furthermore, SC formulations are fully optimized for low-volume aerial spraying (UAV drones), which require clog-free nozzle performance.
Our technical active ingredients (TDZ 98% TC and Diuron 97% TC) undergo multi-stage crystallization and high-performance liquid chromatography (HPLC) testing. We enforce strict limits on unreacted intermediates and isomeric by-products, ensuring compliance with FAO international specifications and local registration requirements.
We supply a full suite of regulatory documentation including GLP 5-batch analysis reports, toxicology dossiers, ecotox studies, Certificate of Analysis (COA), Material Safety Data Sheets (MSDS), Certificate of Free Sale (CFS), and ICAMA certification.
When stored in original sealed UN-rated packaging in a cool, dry, well-ventilated warehouse (below 35°C), the chemical stability and physical suspensibility of our TDZ+Diuron SC and WDG products remain fully guaranteed for 2 years from the date of manufacture.
Explore our full line of wholesale insecticides, herbicides, and plant growth regulators.
Awiner Biotech
